Germany - Institute of Pharmacology and Toxicology, Bonn

The Institute is located at the Biomedical Center (BMC) at the campus of the University Hospital Bonn.

Prof. Dr. med. Alexander Pfeifer
Speaker of the Network

Head of the Institute of Pharmacology and Toxicology
Rheinische Friedrich-Wilhelms-University Bonn
BMZ 2G014/15
Sigmund-Freud-Str. 25
D-53105 Bonn


Tel: +49-228-287-51300
Fax: +49-228-287-51301


Key research interests

- NO/cGMP-signaling cascade – cGMP-dependent proteinkinase; cell- and animal models

- Metabolism: differentiation and function of brown and white adipose tissue

- Viral vectors: focus lentiviral vectors; lentiviral transgenesis (generation of transgenic animals using lentiviral gene transfer)

- RNA-interference: siRNA-based therapies; the role of microRNAs in neurodegeneration und stem cell differentiation

- Neurodegeneration – development of new therapies

- Drug targeting - nanomedicine



- Viral vector platform

- Model systems: lentiviral transgenesis; knockout-mice

- State-of-the-art molecular biology

- Stem cells (MSCs, ES cells)


Important network projects of the Institute of Pharmacology & Toxicology:

-   PharmaCenter Bonn
-   Research Training Group 1873
-   BIGS DrugS
-   BMBF funded Neuroalliance
-   DAAD Research Network Europe-Japan: Nanoparticle for Biomedicine

Institute of Pharmacology and Toxicology